Absolutely! To add additional fields on the Quote Creation Screen, follow these steps.


Setup-->Customize-->Quotes-->Field Sets


Create a new Field Set and make sure the API Name is "Quote_Create".

 

 



Add your fields into the Field Set and click "Save". Make sure you don't add too many fields, the intent is to keep the create screen very simple!




 NOTE: You can also follow the same process for adding fields to Opportunity entry screen. See this article.